Articles Tagged With:
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Direct Oral Anticoagulants vs. Warfarin When Treating Renal Dysfunction
A patient-level meta-analysis of five pivotal trials of direct oral anticoagulants (DOACs) vs. warfarin for patients with atrial fibrillation and creatinine clearance levels ranging from normal to 25 mL/min revealed standard-dose DOACs exhibit superior safety and efficacy compared to adjusted-dose warfarin and lower-dose DOACs.
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The Best Use of Statins in Patients with Coronary Artery Disease
A randomized, multicenter study of high-intensity statin therapy to a treat-to-target approach in coronary artery disease patients showed no difference in three-year outcomes. These results suggest treating to a target may be more suitable to individual patients compared to blanket high-intensity statin use.
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A Promising Frontier in Alzheimer’s Treatment
In a multicenter, head-to-head trial, donanemab demonstrated superiority over aducanumab for early symptomatic Alzheimer’s disease patients.
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Direct Oral Anticoagulants vs. Warfarin When Treating Renal Dysfunction
A patient-level meta-analysis of five pivotal trials of direct oral anticoagulants (DOACs) vs. warfarin for patients with atrial fibrillation and creatinine clearance levels ranging from normal to 25 mL/min revealed standard-dose DOACs exhibit superior safety and efficacy compared to adjusted-dose warfarin and lower-dose DOACs.
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Patients with COVID-19 on ECMO Therapy Benefit from Early Guided Palliative Care Communication
Patients with severe COVID-19 acute respiratory distress syndrome that require extracorporeal membrane oxygenation support can benefit from implementing palliative care communication early in their treatment course.
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Cultural Sensitivity in End-of-Life Discussions in the Intensive Care Unit
When clinicians treat patients and communicate with families who come from cultures that are different from their own, cultural sensitivity can improve the experience for families.
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Preconception Hepatitis B and Congenital Heart Disease
A new study suggests that both women and men who have had hepatitis B infection prior to conceiving offspring are more likely to give birth to children with congenital heart disease.
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Maternal, Fetal, and Infant Implications of a Positive Syphilis Screening During Pregnancy
Although syphilis screening during pregnancy is effective in identifying maternal syphilis, it is not without consequences. False-positive syphilis testing can result in unwarranted antibiotic therapy; re-screening based on risk is not always consistent, and among pregnant women who truly test positive to syphilis, treatment is not always optimized to prevent congenital syphilis.
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Barriers to Urogynecologic Care
There is a paucity of literature on barriers to urogynecologic care in racial/ethnic minorities. Continued evaluation is needed to better understand the unique barriers to urogynecologic care in these populations.
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Ovarian Torsion: What Is the Best Surgical Management Strategy?
In this national retrospective cohort study from 2008 to 2020, there were 1,791 surgeries for adnexal torsion, with 30.3% involving ovarian conservation and the remainder undergoing oophorectomy. The proportion of oophorectomies compared to ovarian conservation decreased slightly over the study period (average decrease, -1.6% per year; 95% confidence interval, -3.0%- to -0.22%).